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Search Results for " colony stimulating factor 1 receptor "

ターゲット

阻害剤

1752

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T5586	CFMS Receptor Inhibitor II		c-Fms
	cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor		c-Fms
T10894	CSF1R-IN-1		c-Fms
	CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.		c-Fms
TQ0015	PRN1371		c-Fms , FGFR , CSF-1R
	PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).		c-Fms , FGFR , CSF-1R
T14380	AZD7507		CSF-1R , HER , Sodium Channel
	AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.		CSF-1R , HER , Sodium Channel
T6119	Sotuletinib	BLZ945	c-Fms , CSF-1R
	Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.		c-Fms , CSF-1R
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T10652	Vimseltinib	DCC-3014	c-Fms , CSF-1R , c-Kit
	Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).		c-Fms , CSF-1R , c-Kit
T2115	Pexidartinib	PLX-3397	Apoptosis , c-Fms , FLT , CSF-1R , c-Kit
	Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.		Apoptosis , c-Fms , FLT , CSF-1R , c-Kit
T7100	PLX5622	PLX-5622	c-Fms , CSF-1R
	PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.		c-Fms , CSF-1R
T2624	OSI-930	OSI 930	Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T2659	GW2580	GW 2580,SC-203877	c-Fms
	GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.		c-Fms
T35570	Chiauranib	CS2164	c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
	Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...		c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
T4315	Ki20227		c-Fms , VEGFR , CSF-1R , PDGFR , c-Kit
	Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR2(IC50: 12 nM) and c-Kit/PDGFRβ(IC50: 451/217 nM), respectively.		c-Fms , VEGFR , CSF-1R , PDGFR , c-Kit
T15199	Edicotinib	JNJ-527,JNJ-40346527	c-Fms , FLT , CSF-1R , c-Kit
	Edicotinib (JNJ-527) is a brain penetrant and orally active inhibitor of the colony-stimulating factor-1 receptor (IC50: 3.2 nM). It shows less inhibitory effects on KIT and FLT3 (IC50: 20 nM and 190 nM). It has the pote...		c-Fms , FLT , CSF-1R , c-Kit
T6930	Pazopanib Hydrochloride	GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala	c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, resp...		c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T6289	Dovitinib	TKI258,CHIR-258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T2514	Linifanib	ABT-869,RG3635,AL-39324	Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T6028	PF 477736	PF 00477736,PF-477736,PF-736,PF-00477736,PF477736	c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
	PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T1925	PLX647		c-Fms , c-Kit
	PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).		c-Fms , c-Kit
T76776	Emactuzumab	RO 5509554,RG 7155	c-Fms , TAM Receptor
	Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating fa...		c-Fms , TAM Receptor
T11390	GENZ-882706	RA03546849	CSF-1R
			CSF-1R
T10647	C-Fms-IN-8		CSF-1R
	c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.		CSF-1R
T10644	C-Fms-IN-10		Others
	c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.		Others
T11729	JTE-952		Histamine Receptor
	JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , resp...		Histamine Receptor
T61554	CSF1R-IN-13
	CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell...
T76908	Anumigilimab
	Anumigilimab (CSL-324) is a humanized IgG2a monoclonal antibody (mAb) targeting the human granulocyte colony-stimulating factor (G-CSF) receptor, utilized to elevate neutrophil counts at inflammation sites [1] [2].
T70444	Edicotinib HCl
	Edicotinib, also known as JNJ-40346527, is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. FMS tyrosine kinase inhibitor JNJ-40...
T71400	Quizartinib HCl
	Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III recept...
T77172	Eflapegrastim
	Eflapegrastim, a humanized IgG4 monoclonal antibody and granulocyte colony-stimulating factor (G-CSF), targets the G-CSF receptor (c-Fms). It promotes the proliferation and differentiation of neutrophil progenitor cells,...

Compounds

cFMS Receptor Inhibitor II

Target: c-Fms, FGFR, CSF-1R

AZD7507

T14380

Synonym:

Target: CSF-1R, HER, Sodium Channel

Sotuletinib

T6119

Synonym: BLZ945

Target: c-Fms, CSF-1R

CSF1R-IN-2

T13194

Synonym:

Target: c-Fms, c-Met/HGFR, Src

Vimseltinib

T10652

Synonym: DCC-3014

Target: c-Fms, CSF-1R, c-Kit

Pexidartinib

T2115

Synonym: PLX-3397

Target: Apoptosis, c-Fms, FLT, CSF-1R, c-Kit

PLX5622

T7100

Synonym: PLX-5622

Target: c-Fms, CSF-1R

OSI-930

T2624

Synonym: OSI 930

Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit

GW2580

T2659

Synonym: GW 2580,SC-203877

Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase

Ki20227

T4315

Synonym:

Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit

Edicotinib

T15199

Synonym: JNJ-527,JNJ-40346527

Target: c-Fms, FLT, CSF-1R, c-Kit

Pazopanib Hydrochloride

T6930

Synonym: GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala

Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Dovitinib

T6289

Synonym: TKI258,CHIR-258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Linifanib

T2514

Synonym: ABT-869,RG3635,AL-39324

Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy

PF 477736

T6028

Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase

Synonym: RO 5509554,RG 7155

Target: c-Fms, TAM Receptor

Target: Histamine Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01037	CSF1R Protein (Met1-Glu512), Human, Recombinant (His)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05040	CSF1R Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05043	CSF1R Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-03920	CSF1R Protein, Rat, Recombinant (hFc)	Rat	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-03734	CSF1R Protein, Rat, Recombinant (His)	Rat	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-00881	CSF1R Protein, Human, Recombinant	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05429	CSF1R Protein, Human, Recombinant (hFc)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05045	CSF1R Protein, Human, Recombinant (Domain I&II&III, His)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-06389	CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05264	CSF1R Protein, Human, Recombinant (mFc)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-04938	CSF1R Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-01833	CSF1R Protein, Mouse, Recombinant (His)	Mouse	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-05436	CSF1R Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPJ-01419	CSF1R Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPJ-01418	CSF1R Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPY-05513	CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-06384	CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-04358	CSF1R Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPH-00354	CSF1R Protein, Feline, Recombinant (His & SUMO)	Feline	E. coli
	Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially monon...
TMPY-00986	IL-34 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocyt...
TMPY-05296	IL-34 Protein, Human, Recombinant (His)	Human	CHO
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocyt...
TMPY-00464	M-CSF/CSF1 Protein, Mouse, Recombinant	Mouse	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPY-03537	M-CSF/CSF1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-05335	M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-04229	M-CSF/CSF1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-04705	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-05181	M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-04704	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-01591	CD200RLa Protein, Human, Recombinant (His)	Human	HEK293
	Cell surface glycoprotein CD2 receptor 2, also known as Cell surface glycoprotein CD2 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD2 receptor-like 2, CD2Rla, CD2R1L and CD2R2, is a single-pass type I m...
TMPY-01757	CD200RLa Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Cell surface glycoprotein CD2 receptor 2, also known as Cell surface glycoprotein CD2 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD2 receptor-like 2, CD2Rla, CD2R1L and CD2R2, is a single-pass type I m...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-01023	CD38 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05239	HER2/ERBB2 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-05364	CD8 alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01226	CD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01050	Cadherin 6/CDH6 Protein, Human, Recombinant (His)	Human	HEK293
	Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc)	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01938	CD98 Protein, Human, Recombinant (His)	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
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